2025 Global AIDS Update — AIDS, Crisis and the Power to Transform

This executive summary reports a historic funding crisis that threatens to reverse decades of progress in the HIV response. It notes that new HIV infections fell 40% and AIDS-related deaths 56% since 2010, with 32 million people on treatment by 2024. However, sudden reductions in international financing—including major cuts to PEPFAR—risk causing 6 million additional infections and 4 million more AIDS deaths by 2029. The summary also highlights emerging long‑acting prevention tools, such as injectable PrEP, and calls for urgent solidarity, domestic investment, and strengthened community-driven responses to sustain gains and aim for ending AIDS by 2030.