This article from Intersecção – Política de Drogas, Uso da terra e Justiça Climática analyzes the socioeconomic and environmental impacts of prohibiting coca and cocaine production in the Amazon Basin and Brazil. It identifies drug prohibition as a contributing factor to deforestation, armed violence, and human rights violations, linking these to broader climate and territorial justice concerns. The findings underscore the need to integrate drug policy reform and ecological harm reduction into climate mitigation and adaptation strategies.